MSR-seq™ Publications

See how scientists are using MSR-seq™

High-fat diet driven post-operative colon cancer recurrence is dependent upon genetic susceptibility to deoxycholic acid

Morgan et al., 2025

Cancer Letters

In vivo structure profiling reveals human cytosolic and mitochondrial tRNA structurome and interactome in response to stress

Pena et al., 2025

Nature Communications

Structural basis of antiphage defense by an ATPase-associated reverse transcriptase

George et al., 2025

bioRxiv

Mammalian queuosine tRNA modification impacts translation to enhance cell proliferation and MHC-II expression

Zbibley et al., 2025

Journal of Molecular Biology

Fungal-derived tRNAs are expressed and aminoacylated in orchid mitochondria

Warren et al., 2025

Molecular Biology and Evolution

Bioinformatics of simultaneous, quantitative measurements of full-length tRNA and tRNA fragments by MSR sequencing

Frietze & Pan, 2025

Methods in enzymology

Modifications in the T arm of tRNA globally determine tRNA maturation, function, and cellular fitness

Schultz et al., 2024

Proceedings of the National Academy of Sciences

Prokaryotic RNA N1-Methyladenosine Erasers Maintain tRNA m1A Modification Levels in Streptomyces venezuelae

Foo et al., 2024

ACS chemical biology

Design, construction, and functional characterization of a tRNA neochromosome in yeast

Schindler et al., 2023

Cell

Single-read tRNA-seq analysis reveals coordination of tRNA modification and aminoacylation and fragmentation

Hernandez-Alias et al., 2023

Nucleic Acids Research

Analysis of queuosine and 2-thio tRNA modifications by high throughput sequencing

Katanski et al., 2022

Nucleic Acids Research

tRNA abundance, modification and fragmentation in nasopharyngeal swabs as biomarkers for COVID-19 severity

Katanski et al., 2022

Frontiers in Cell and Developmental Biology